Anaesthesia for Obstetrics and Gynaecology: Fundamentals of by Robin Russell

By Robin Russell

This newest contribution to the FAAM sequence offers a finished and recent dialogue of anaesthetic administration in being pregnant, in the course of supply, and in sufferers present process gynaecological surgical procedure. With authoritative contributions from foreign specialists it's a useful reference for all anaesthetists and expert clinicians.

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In: Shnider S, Levinson G, eds. Anesthesia for obstetrics. Baltimore: Williams and Williams, 1993:259-80. 85 Duncan PG, Pope WDB, Cohen MM, Greer N. Fetal risk of anesthesia and surgery during pregnancy. Anesthesiology 1986;64:790-4. 86 Shiono PH, Mills JL. Oral clefts and diazepam use during pregnancy. N E n g l J Med 1984;311:919-920. 87 Reddy BK, Pizer B, Bull PT. Neonatal serum cortisol suppression by etomidate compared with thiopentone, for elective caesarean section. E u r J Arraesrhesiol 1988;5: 17 1.

48 Gerbasi FR, Bottoms S, Farag A, Mammen EF. Changes in hemostasis activity dunng delivery and the immediate postpartum period. A m J Obstet Gynecol 1990;162: 1158-63. 27 ANAESTHESIA FOR ORSI'ETRICS AND GYNAECOLOGY 49 Talbert LM, Langdell RD. Normal values of certain blood factors in the blood clotting mechanism in pregnancy. A m 3 Obstet Gynecol 1964;90:44-50. 50 Bonnar J, McNicol GP, Douglas AS. Coagulation and fibrinolytic mechanism during and after normal childbirth. B M J 1970;2:200-3. 51 Gerbasi FR, Bottoms S, Farag A, Mammen EF.

Ranitidine and cimetidine are not known to be harmful but caution is advised with chronic exposure to cimetidine because of known androgenic effects in adults. Induction agents Thiopentone has been used for many years and does not appear to be associated with fetal abnormalities although formal studies have not been conducted. Chronic exposure to barbiturates may be associated with fetal anomalies although evidence is contradictory. Reproductive studies in animals have suggested that propofol may lead to delayed or abnormal ossification.

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