By W. Zimmerli
Bone and Joint Infections is the 1st e-book to take a multidisciplinary method of protecting the reasons and therapy of osteomyelitis and septic arthritis. right and speedy analysis of bone and joint an infection calls for the enter of numerous experts, and Bone and Joint Infection takes a similarly collaborative and comprehensive approach, together with chapters from a diverse staff of clinicians, researchers, and surgeons.
Covering either the elemental microbiology and medical points of bone and joint an infection, this ebook could be a important source either for researchers within the lab and for physicians and surgeons looking a complete reference on osteomyelitis and septic arthritis.
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Additional info for Bone and Joint Infections: From Microbiology to Diagnostics and Treatment
Aureus Candida species Serratia marcescens Spinal surgery Coagulase-negative staphylococci S. aureus Propionibacterium acnes Aerobic Gram-negative bacilli staphylococci or P. acnes, to cause infection. Staphylococci (S. aureus and coagulasenegative staphylococci, especially S. 2). Other bacteria, including rarely mycobacteria and occasionally fungi, cause the rest of the cases. Approximately 20% of PJI cases are polymicrobial, and in about 7% there is no growth of any microorganism. PJI after Knee Arthroplasty The most common organisms associated with prosthetic knee infection are S.
45] compared broad-range PCR of material dislodged from replaced orthopedic implants using vortexing and sonication (sonicate fluid) with synovial fluid culture, tissue culture and culture of sonicate fluid. 4%). Data from studies evaluating broadrange PCR of tissue for PJI diagnosis may be conflicting because of technical differences and differences in criteria used for diagnosis of PJI. De Man et al.  compared 16S rRNA PCR to culture using synovial fluid and periprosthetic tissue; PCR and culture sensitivity were 50 and 58%, respectively.
1. Recently, the Musculoskeletal Infection Society (MSIS) and the Infectious Diseases Society of America (IDSA) have released slightly different definitions of PJI [32, 33]. According to the MSIS criteria, definite PJI exists in the presence of (1) a sinus tract communicating with the prosthesis; or (2) positive cultures for the same organism from at least two tissue or fluid samples from the joint; or (3) four of the following: (a) elevated serum ESR and CRP, (b) elevated synovial leukocyte count, (c) elevated synovial fluid neutrophil percentage, (d) purulence in the joint space, (e) growth of a microorganism in one periprosthetic tissue or fluid culture, or (f) greater than five neutrophils per high-power field in five high-power fields on periprosthetic tissue histopathology .