By Bernard Ravina; et al
''Translating laboratory discoveries into profitable therapeutics will be tricky. scientific Trials in Neurology goals to enhance the potency of medical trials and the advance of interventions with a purpose to improve the improvement of recent remedies for neurologic illnesses. It introduces the reader to the major options underpinning trials within the neurosciences. This quantity tackles the demanding situations of developing cures for neurologic problems from size of brokers within the anxious method to the development of medical symptoms via illustrating particular research designs and their functions to assorted healing parts. medical Trials in Neurology covers key matters in part I, II and III scientific trials, in addition to post-marketing protection surveillance. subject matters addressed comprise regulatory and implementation matters, final result measures and customary difficulties in drug improvement. Written through a multidisciplinary crew, this accomplished advisor is vital studying for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and medical researchers within the pharmaceutical industry''-- Read more...
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Additional info for Clinical trials in neurology : design, conduct, analysis
Conidence in the accuracy of the safety 14 and tolerability proile is derived from the number of patients exposed and their duration of treatment with a medication. For chronically administered drugs for non-life threatening conditions, the International Committee on Harmonisation (ICH) Guidelines recommend an overall exposure of 1500 patients with 300–600 patients exposed for 6 months and 100 patients exposed for one year . hese exposures must occur at the dose or dose range believed to be eicacious.
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