From neuroscience to neurology by Waxman S.

By Waxman S.

The sector of neurology is being remodeled, from a therapeutically nihilistic self-discipline with few potent remedies, to a healing strong point which deals new, powerful remedies for problems of the mind and spinal twine. This striking transformation has bridged neuroscience, molecular drugs, and medical research, and represents a tremendous triumph for biomedical learn. This booklet, which includes chapters through greater than 29 the world over famous professionals who've made significant contributions to neurotherapeutics, tells the tales of the way new remedies for disabling problems of the anxious method, resembling stroke, a number of sclerosis, Parkinson's sickness, and migraine, have been built, and explores evolving subject matters and applied sciences that supply wish for much more powerful remedies and finally remedies for at present untreatable issues of the mind and spinal wire. the 1st a part of this e-book experiences the improvement of latest cures in neurology, from their inception when it comes to simple technological know-how to their advent into the medical global. It additionally explores evolving topics and new applied sciences. This booklet might be of curiosity to each person - clinicians and easy scientists alike - drawn to ailments of the mind and spinal twine, and within the quest for brand spanking new remedies for those issues. * offers the evolution of the sector of neurology right into a healing self-discipline * Discusses classes discovered from earlier successes and purposes to ongoing paintings* Explores the way forward for this box

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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report, JAMA 289:2560-2572. Cornu C et al. (2000). Streptokinase in acute ischemic stroke: an individual patient data meta-analysis : The Thrombolysis in Acute Stroke Pooling Project, Stroke 31:1555-1560. Dahlof B et al. (2002). Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol, Lancet 359:9951003.

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2002) did aim to determine whether the ARB, losartan, had cardiovascular benefits independent of BP-lowering. LIFE was an investigatorinitiated, double-blind, randomized, controlled trial of losartan (the first angiotensin II type 1 receptor blocker) vs atenolol in patients with hypertension and left ventricular hypertrophy for the prevention of cardiovascular morbidity and death. Atenolol was chosen as the comparator because it was recognized worldwide as a first-line treatment for hypertension with similar antihypertensive efficacy to losartan.

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